Altered TCR signaling from geometrically repatterned immunological synapses.

The immunological synapse is a specialized cell-cell junction that is defined by large-scale spatial patterns of receptors and signaling molecules yet remains largely enigmatic in terms of formation and function. We used supported bilayer membranes and nanometer-scale structures fabricated onto the...

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Hlavní autoři: Mossman, K, Campi, G, Groves, J, Dustin, M
Médium: Journal article
Jazyk:English
Vydáno: 2005