DNA duplexes stabilized by modified monomer residues: synthesis and stability
The synthesis of a series of 2′-deoxyuridine analogues modified at the 5-position and a series of 2′-deoxypurines modified at the 8-position is described. Ultraviolet melting studies have been used to assess the stability of DNA duplexes 12- and 8-residues in length that contain these modifications....
Autori principali: | , , |
---|---|
Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
1998
|