Neuraminidases 3 and 4 regulate neuronal function by catabolizing brain gangliosides
Sialylated glycolipids, gangliosides play an essential role in the central nervous system regulating recognition and signaling in neurons. Metabolic blocks in processing and catabolism of gangliosides result in development of severe neurological disorders, gangliosidoses manifesting with neurodegene...
Hauptverfasser: | Pan, X, De Britto Pará De Aragão, C, Velasco-Martin, J, Priestman, D, Wu, H, Takahashi, K, Yamaguchi, K, Sturiale, L, Garozzo, D, Platt, F, Lamarche-Vane, N, Morales, C, Miyagi, T, Pshezhetsky, A |
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Format: | Journal article |
Veröffentlicht: |
Federation of American Society of Experimental Biology (FASEB)
2017
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