Neuraminidases 3 and 4 regulate neuronal function by catabolizing brain gangliosides

Neuraminidases 3 and 4 regulate neuronal function by catabolizing brain gangliosides

Sialylated glycolipids, gangliosides play an essential role in the central nervous system regulating recognition and signaling in neurons. Metabolic blocks in processing and catabolism of gangliosides result in development of severe neurological disorders, gangliosidoses manifesting with neurodegene...

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Detalhes bibliográficos
Main Authors: Pan, X, De Britto Pará De Aragão, C, Velasco-Martin, J, Priestman, D, Wu, H, Takahashi, K, Yamaguchi, K, Sturiale, L, Garozzo, D, Platt, F, Lamarche-Vane, N, Morales, C, Miyagi, T, Pshezhetsky, A
Formato: Journal article
Publicado em: Federation of American Society of Experimental Biology (FASEB) 2017

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