Sperm express a Ca2+-regulated NAADP synthase.

Sperm express a Ca2+-regulated NAADP synthase.

NAADP (nicotinic acid-adenine dinucleotide phosphate), the most potent Ca2+-mobilizing second messenger, is active in a wide range of organisms and cell types. Until now, all NAADP-producing enzymes have been thought to be members of the ADP-ribosyl cyclase family. ADP-ribosyl cyclases exhibit promi...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Vasudevan, SR, Galione, A, Churchill, G
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2008

Eitemau Tebyg

Sperm expresses surface bound base exchange enzyme that selectively synthesises NAADP
gan: Vasudevan, SR, et al.
Cyhoeddwyd: (2005)

Sperm expresses a surface bound base exchange enzyme that selectively synthesises NAADP and is controlled by calcium.
gan: Vasudevan, SR, et al.
Cyhoeddwyd: (2006)

Regulation and pathway of NAADP synthesis in sea urchin sperm
gan: Lewis, A, et al.
Cyhoeddwyd: (2006)

Coordination of Ca2+ signalling by NAADP.
gan: Patel, S, et al.
Cyhoeddwyd: (2001)

Sperm deliver a new second messenger: NAADP.
gan: Churchill, G, et al.
Cyhoeddwyd: (2003)

Calcium stimulates the synthesis of nicotinic acid adenine dinucleotide phosphate (NAADP) in sea urchin sperm
gan: Lewis, A, et al.
Cyhoeddwyd: (2005)

NAADP induces Ca2+ oscillations via a two-pool mechanism by priming IP3- and cADPR-sensitive Ca2+ stores.
gan: Churchill, G, et al.
Cyhoeddwyd: (2001)

Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhance the sensitivity of NAADP receptors for their ligand.
gan: Patel, S, et al.
Cyhoeddwyd: (2000)

Cell-permeant NAADP: a novel chemical tool enabling the study of Ca2+ signalling in intact cells.
gan: Parkesh, R, et al.
Cyhoeddwyd: (2008)

Physiological roles of NAADP-mediated Ca2+ signaling.
gan: Galione, A, et al.
Cyhoeddwyd: (2011)

Cell-permeant small-molecule modulators of NAADP-mediated Ca2+ release.
gan: Dowden, J, et al.
Cyhoeddwyd: (2006)

Does NAADP-induced Ca2+ release contribute to glucose-induced (ca(2+))(i) changes in primary mouse pancreatic beta-cell?
gan: Arredouani, A, et al.
Cyhoeddwyd: (2006)

NAADP controls cross-talk between distinct Ca2+ stores in the heart.
gan: Macgregor, A, et al.
Cyhoeddwyd: (2007)

NAADP: a new second messenger for glucose-induced Ca2+ responses in clonal pancreatic beta cells.
gan: Masgrau, R, et al.
Cyhoeddwyd: (2003)

Chemo-enzymatic synthesis and biological evaluation of photolabile nicotinic acid adenine dinuclotide phosphate (NAADP+).
gan: Parkesh, R, et al.
Cyhoeddwyd: (2007)

NAADP-induced calcium release in sea urchin eggs.
gan: Galione, A, et al.
Cyhoeddwyd: (2000)

NAADP regulates human platelet function.
gan: Coxon, C, et al.
Cyhoeddwyd: (2012)

The luminal Ca2+ chelator, TPEN, inhibits NAADP-induced Ca2+ release
gan: Morgan, A, et al.
Cyhoeddwyd: (2012)

The luminal Ca(2+) chelator, TPEN, inhibits NAADP-induced Ca(2+) release.
gan: Morgan, A, et al.
Cyhoeddwyd: (2012)

Chemical synthesis of the novel Ca2+ messenger NAADP.
gan: Dowden, J, et al.
Cyhoeddwyd: (2005)

NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs.
gan: Churchill, G, et al.
Cyhoeddwyd: (2002)

NAADP receptors.
gan: Galione, A
Cyhoeddwyd: (2011)

NAADP Receptors
gan: Galione, A
Cyhoeddwyd: (2011)

NAADP receptors
gan: Galione, A
Cyhoeddwyd: (2019)

Analogues of the nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist Ned-19 indicate two binding sites on the NAADP receptor.
gan: Rosen, D, et al.
Cyhoeddwyd: (2009)

NAADP, a new intracellular messenger that mobilizes Ca2+ from acidic stores.
gan: Galione, A
Cyhoeddwyd: (2006)

NAADP induces pH changes in the lumen of acidic Ca2+ stores.
gan: Morgan, A, et al.
Cyhoeddwyd: (2007)

Calcium signalling by nicotinic acid adenine dinucleotide phosphate (NAADP).
gan: Yamasaki, M, et al.
Cyhoeddwyd: (2005)

Identification of a chemical probe for NAADP by virtual screening.
gan: Naylor, E, et al.
Cyhoeddwyd: (2009)

NAADP receptors.
gan: Galione, A, et al.
Cyhoeddwyd: (2005)

The Involvement of NAADP and Two-Pore Ca2+ Channels in the Cardiac Beta-Adrenergic Response
gan: Bolton, E, et al.
Cyhoeddwyd: (2013)

The NAADP receptor: new receptors or new regulation?
gan: Galione, A, et al.
Cyhoeddwyd: (2005)

NAADP: a novel Ca2+ mobilizing messenger during beta-adrenoceptor stimulation in guinea-pig ventricular myocytes
gan: Yamasaki, M, et al.
Cyhoeddwyd: (2007)

Glucose and NAADP trigger elementary intracellular β-cell Ca2+ signals
gan: Paula Maria Heister, et al.
Cyhoeddwyd: (2021-05-01)

Synthesis, degradation, binding and actions of NAADP in cardiac tissue.
gan: Rakovic, S, et al.
Cyhoeddwyd: (2001)

Recruitment of NAADP-sensitive acidic Ca2+ stores by glutamate.
gan: Pandey, V, et al.
Cyhoeddwyd: (2009)

Rapid, selective and dose-dependent elevation of the second messenger NAADP
gan: Yamasaki, M, et al.
Cyhoeddwyd: (2005)

A novel signalling role for NAADP in arterial smooth muscle
gan: Lim, C, et al.
Cyhoeddwyd: (2013)

NAADP-regulated two-pore channels drive phagocytosis through endo-lysosomal Ca2+ nanodomains, calcineurin and dynamin
gan: Davis, LC, et al.
Cyhoeddwyd: (2020)

Role of NAADP and cADPR in the induction and maintenance of agonist-evoked Ca2+ spiking in mouse pancreatic acinar cells.
gan: Yamasaki, M, et al.
Cyhoeddwyd: (2005)