SCANPS: a web server for iterative protein sequence database searching by dynamic programing, with display in a hierarchical SCOP browser.

SCANPS performs iterative profile searching similar to PSI-BLAST but with full dynamic programing on each cycle and on-the-fly estimation of significance. This combination gives good sensitivity and selectivity that outperforms PSI-BLAST in domain-searching benchmarks. Although computationally expen...

Descrición completa

Detalles Bibliográficos
Main Authors: Walsh, T, Webber, C, Searle, S, Sturrock, S, Barton, G
Formato: Journal article
Idioma:English
Publicado: 2008