Bifunctional iminophosphorane catalyzed amide enolization for enantioselective cyclohexadienone desymmetrization.
The organocatalytic enolization of 2-arylacetamides, followed by an enantioselective intramolecular conjugate addition to tethered 2,5-cyclohexadienones, yielding 3D fused N-heterocycles, is described. The transformation represents the first strong activating group-free activation of carboxamides vi...
Prif Awduron: | Poh, CYX, Rozsar, D, Yang, J, Christensen, KE, Dixon, DJ |
---|---|
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
Wiley
2023
|
Eitemau Tebyg
-
Bifunctional iminophosphorane-catalyzed enantioselective sulfa-michael addition to unactivated α,β-unsaturated amides
gan: Rozsar, D, et al.
Cyhoeddwyd: (2022) -
Bifunctional iminophosphorane-catalyzed enantioselective nitroalkane addition to unactivated α,β-unsaturated esters
gan: Rozsar, D, et al.
Cyhoeddwyd: (2023) -
A bifunctional iminophosphorane squaramide catalyzed enantioselective synthesis of hydroquinazolines via intramolecular aza-Michael reaction to α,β-unsaturated esters
gan: Su, G, et al.
Cyhoeddwyd: (2021) -
Bifunctional iminophosphorane superbase catalysed amide enolisation for enantioselective intramolecular reactions
gan: Poh, YXC
Cyhoeddwyd: (2024) -
Bifunctional iminophosphorane catalyzed enantioselective ketimine phospha-Mannich reaction
gan: Robertson, G, et al.
Cyhoeddwyd: (2015)