HLA-B27

HLA-B27

Possession of the human leukocyte antigen (HLA) class I molecule B27 is strongly associated with ankylosing spondylitis (AS), but the pathogenic role of HLA-B27 is unknown. Two broad theories most likely explain the role of HLA-B27 in AS pathogenesis. The first is based on the natural immunological...

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Bibliografiska uppgifter
Huvudupphovsman:	Bowness, P
Materialtyp:	Journal article
Språk:	English
Publicerad:	Annual Reviews 2015

Liknande verk

The KIRs of HLA-B27: the role of HLA-B27 KIR interactions in infection and spondyloarthritis
av: Wong-Baeza, I, et al.
Publicerad: (2011)

The role of HLA-B27 in spondyloarthritis.
av: Allen, R, et al.
Publicerad: (1999)

Jekyll and Hyde: the transformation of HLA-B27.
av: Edwards, J, et al.
Publicerad: (2000)

HLA B27 in health and disease: a double-edged sword?
av: Bowness, P
Publicerad: (2002)

EXPRESSION OF HLA-B27 HEAVY CHAIN FORMS IN ANKYLOSING SPONDYLITIS AND HLA-B27 POSITIVE CELL LINES
av: Rysnik, O, et al.
Publicerad: (2012)

HLA-B27: natural function and pathogenic role in spondyloarthritis.
av: McMichael, A, et al.
Publicerad: (2002)

HLA-B27 transgenic rodents express cell surface HLA-B27 heavy chain homodimers and multimers.
av: Bowness, P, et al.
Publicerad: (2003)

Functional characterisation of HLA-B27 in autoimmunity
av: Kollnberger, S, et al.
Publicerad: (2001)

Residue Cys-67 of HLA-B27 contributes to antigen presentation and T cell recognition of HLA-B27 restricted T cell epitopes.
av: Appel, H, et al.
Publicerad: (2004)

Supplementary figures for "Inhibiting HLA-B27 homdimer-driven immune cell inflammation in Spondyloarthritis"
av: Bowness, P
Publicerad: (2012)

HLA-B-27 heavy chain homodimer formation and natural killer cell family interaction - comparison of two HLA-B-27 subtypes in vitro
av: Giles, J, et al.
Publicerad: (2008)

The solvent-inaccessible Cys67 residue of HLA-B27 contributes to T cell recognition of HLA-B27/peptide complexes.
av: Appel, H, et al.
Publicerad: (2004)

HLA-B27 and disease pathogenesis: new structural and functional insights.
av: Bowness, P, et al.
Publicerad: (1999)

Identification and characterisation of cell surface HLA-B27 homodimers
av: Bird, L, et al.
Publicerad: (2002)

The link between HLA-B27 and SpA--new ideas on an old problem.
av: McHugh, K, et al.
Publicerad: (2012)

DIRECT VISUALIZATION OF HLA-B27 FORMS IN CELL LINES AND SPONDYLOARTHROPATHY TISSUES
av: Rysnik, O, et al.
Publicerad: (2013)

Direct visualisation of HLA-B27 forms in cell lines and Spondyloarthropathy tissues
av: Rysnik, O, et al.
Publicerad: (2013)

HLA-B27 HEAVY CHAIN DIMER EXPRESSION IN SPONDYLOARTHRITIS
av: Rysnik, O, et al.
Publicerad: (2012)

Identification of HLA-B27-restricted peptides from the Chlamydia trachomatis proteome with possible relevance to HLA-B27-associated diseases.
av: Kuon, W, et al.
Publicerad: (2001)

Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply.
av: McHugh, K, et al.
Publicerad: (2014)

HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.
av: Kollnberger, S, et al.
Publicerad: (2004)

Dimers are forever. Expression and recognition of abnormal HLA-B27 in spondylo arthritis
av: Bowness, P, et al.
Publicerad: (2005)

Identification of T cell receptor recognition residues for a viral peptide presented by HLA B27.
av: Bowness, P, et al.
Publicerad: (1994)

The role of HLA-B27 interactions with natural killer receptors in the pathogenesis of spondyloarthritis
av: Kollnberger, S, et al.
Publicerad: (2007)

HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats.
av: Osiris Marroquin Belaunzaran, et al.
Publicerad: (2015-01-01)

IDENTIFICATION OF T-CELL RECEPTOR RECOGNITION RESIDUES FOR AN INFLUENZA-VIRUS NONAMER PEPTIDE EPITOPE PRESENTED BY HLA B27
av: Bowness, P, et al.
Publicerad: (1995)

HLA-B27-RESTRICTED PEPTIDE PRESENTATION TO CYTOTOXIC T-CELLS IN REACTIVE ARTHRITIS
av: Bowness, P, et al.
Publicerad: (1995)

Molecular determinants for KIR3DL2 binding to HLA-B27 and other HLA-class I ligands
av: Hatano, H, et al.
Publicerad: (2013)

Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide.
av: Kollnberger, S, et al.
Publicerad: (2007)

HLA-B27 homodimers differ in their interactions with LILRB1, LILRB2, KIR3DL1 and KIR3DL2 compared to HLA-B27 heterotrimers
av: Giles, J, et al.
Publicerad: (2010)

ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients.
av: Robinson, P, et al.
Publicerad: (2015)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
av: Bowness, P, et al.
Publicerad: (2010)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
av: Bowness, P, et al.
Publicerad: (2010)

Cell-surface expression and immune receptor recognition of HLA-B27 homodimers.
av: Kollnberger, S, et al.
Publicerad: (2002)

HLA B27 can form heavy chain homodimers in vivo and in vivo, possible role of cys 67.
av: Bowness, P, et al.
Publicerad: (1998)

The pathogenesis of spondyloarthritides - HLA-B-27 homodimer expression on human monocyte/macrophage cell lines
av: McHugh, K, et al.
Publicerad: (2008)

THE ARTHRITIS-ASSOCIATED HLA-B(star)27:05 FORMS MORE CELL SURFACE B27 DIMER AND FREE HEAVY CHAIN LIGANDS FOR KIR3DL2 AND LILRB2 IMMUNORECEPTORS THAN HLA(star)B27:09
av: Shaw, J, et al.
Publicerad: (2013)

HLA class I typing by PCR: HLA-B27 and an African B27 subtype.
av: Hill, A, et al.
Publicerad: (1991)

Genotyping HLA-B27 in spondyloarthropathies.
av: Brown, M, et al.
Publicerad: (1998)

THE ROLE OF HLA-B27 KIR3DL2 INTERACTIONS IN THE PATHOGENESIS OF SPONDYLOARTHRITIS
av: Kollnberger, S, et al.
Publicerad: (2012)