Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer

Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer

Up to 10% of cases of gastric cancer are familial, but so far, only mutations in CDH1 have been associated with gastric cancer risk. To identify genetic variants that affect risk for gastric cancer, we collected blood samples from 28 patients with hereditary diffuse gastric cancer (HDGC) not associa...

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主要な著者: Sahasrabudhe, R, Lott, P, Bohorquez, M, Toal, T, Estrada, A, Suarez, J, Brea-Fernández, A, Cameselle-Teijeiro, J, Pinto, C, Ramos, I, Mantilla, A, Prieto, R, Corvalan, A, Norero, E, Alvarez, C, Tapia, T, Carvallo, P, Gonzalez, L, Cock-Rada, A, Solano, A, Neffa, F, Della Valle, A, Yau, C, Soares, G, Borowsky, A, Hu, N, He, L, Han, X, Latin American Gastric Cancer Genetics Collaborative Group, Taylor, P, Goldstein, A, Torres, J, Echeverry, M, Ruiz-Ponte, C, Teixeira, M, Carvajal Carmona, L
フォーマット: Journal article
言語:English
出版事項: AGA Institute 2016

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