Age-dependent decline in cardiac function in guanidinoacetate-N-methyltransferase knockout mice

Age-dependent decline in cardiac function in guanidinoacetate-N-methyltransferase knockout mice

Aim:Guanidinoacetate N-methyltransferase (GAMT) is the second essential enzyme in creatine (Cr) biosynthesis. Short-term Cr deficiency is metabolically well tolerated as GAMT-/- mice exhibit normal exercise capacity and response to ischemic heart failure. However, we hypothesized long-term consequen...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Aksentijević, D, Zervou, S, Eykyn, TR, McAndrew, DJ, Lygate, CA, Wallis, J, Schneider, JE, Neubauer, S
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	Frontiers Media 2019

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