Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons

Cohesin is a highly conserved multisubunit complex that holds sister chromatids together in mitotic cells. At the metaphase to anaphase transition, proteolytic cleavage of the α kleisin subunit (Rad21) by separase causes cohesin's dissociation from chromosomes and triggers sister-chromatid disj...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Pauli, A, Althoff, F, Oliveira, R, Heidmann, S, Schuldiner, O, Lehner, C, Dickson, B, Nasmyth, K
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2008