Schwann cell nodal membrane disruption triggers bystander axonal degeneration in a Guillain-Barré syndrome mouse model

In Guillain-Barré syndrome (GBS), both axonal and demyelinating variants can be mediated by complement-fixing anti–GM1 ganglioside autoantibodies that target peripheral nerve axonal and Schwann cell (SC) membranes, respectively. Critically, the extent of axonal degeneration in both variants dictates...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: McGonigal, R, Campbell, CI, Barrie, JA, Yao, D, Cunningham, ME, Crawford, CL, Rinaldi, S, Rowan, EG, Willison, HJ
Format: Journal article
Język:English
Wydane: American Society for Clinical Investigation 2022