Iron-deficiency anemia results in transcriptional and metabolic remodeling in the heart toward a glycolytic phenotype
Iron deficiency is the most prevalent micronutrient disorder globally. When severe, iron deficiency leads to anemia, which can be deleterious to cardiac function. Given the central role of iron and oxygen in cardiac biology, multiple pathways are expected to be altered in iron-deficiency anemia, and...
Hoofdauteurs: | Chung, YJ, Swietach, P, Curtis, MK, Ball, V, Robbins, PA, Lakhal-Littleton, S |
---|---|
Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
Frontiers Media
2021
|
Gelijkaardige items
-
Iron-deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity
door: Chung, Y, et al.
Gepubliceerd in: (2019) -
Iron deficiency and supplementation in heart failure
door: Lakhal-Littleton, S, et al.
Gepubliceerd in: (2024) -
Iron Deficiency as a Therapeutic Target in Cardiovascular Disease
door: Samira Lakhal-Littleton
Gepubliceerd in: (2019-08-01) -
The interplay between iron and oxygen homeostasis with a particular focus on the heart
door: Lakhal-Littleton, S, et al.
Gepubliceerd in: (2017) -
The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload
door: Mohammad, G, et al.
Gepubliceerd in: (2021)