Multi-center evaluation of the fully automated PCR-based Idylla™ KRAS mutation assay for rapid KRAS mutation status determination on formalin-fixed paraffin-embedded tissue of human colorectal cancer

Multi-center evaluation of the fully automated PCR-based Idylla™ KRAS mutation assay for rapid KRAS mutation status determination on formalin-fixed paraffin-embedded tissue of human colorectal cancer

<p>Since the advent of monoclonal antibodies against epidermal growth factor receptor (EGFR) in colorectal cancer therapy, the determination of RAS mutational status is needed for therapeutic decision-making. Most prevalent in colorectal cancer are <em>KRAS</em> exon 2 mutations (4...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Solassol, J, Vendrell, J, Märkl, B, Haas, C, Bellosillo, B, Montagut, C, Smith, M, O'Sullivan, B, D'Haene, N, Le Mercier, M, Grauslund, M, Melchior, L, Burt, E, Cotter, F, Stieber, D, Schmitt, F, Motta, V, Lauricella, C, Colling, R, Soilleux, E, Fassan, M, Mescoli, C, Collin, C, Pagès, J, Sillekens, P
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	Public Library of Science 2016

Παρόμοια τεκμήρια

Multi-Center Evaluation of the Fully Automated PCR-Based Idylla™ KRAS Mutation Assay for Rapid KRAS Mutation Status Determination on Formalin-Fixed Paraffin-Embedded Tissue of Human Colorectal Cancer.
ανά: Jérôme Solassol, κ.ά.
Έκδοση: (2016-01-01)

Spatial heterogeneity of KRAS mutations in colorectal cancers in northern France
ανά: Turpin A, κ.ά.
Έκδοση: (2019-09-01)

KRAS Mutation in Serous Borderline Tumor of the Testis: Report of a Case and Review of the Literature
ανά: Sarah Bouri, κ.ά.
Έκδοση: (2020-01-01)

KRAS mutations and endometriosis burden of disease
ανά: Natasha L Orr, κ.ά.
Έκδοση: (2023-07-01)

Clinical Significance of the KRAS Mutation
ανά: Sead Beganovic
Έκδοση: (2010-10-01)

P53 and PIK3CA Mutations in KRAS/HER2 Negative Ovarian Intestinal-Type Mucinous Carcinoma Associated with Mature Teratoma
ανά: Sarah Bouri, κ.ά.
Έκδοση: (2020-01-01)

Mutations in the KRAS gene in ovarian tumors.
ανά: Wiesława Niklińska, κ.ά.
Έκδοση: (2009-12-01)

KRAS mutation in biliary tract cholangiocarcinoma
ανά: Sora Yasri
Έκδοση: (2017-03-01)

The origins and genetic interactions of KRAS mutations are allele- and tissue-specific
ανά: Joshua H. Cook, κ.ά.
Έκδοση: (2021-03-01)

KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice
ανά: Jasmine C. Wong, κ.ά.
Έκδοση: (2020-11-01)

Somatic mutation detection and KRAS amplification in testicular germ cell tumors
ανά: Eduardo R. M. Cabral, κ.ά.
Έκδοση: (2023-03-01)

Codon-specific KRAS mutations predict survival in advanced pancreatic cancer
ανά: A. Boilève, κ.ά.
Έκδοση: (2024-03-01)

Capturing the primordial Kras mutation initiating urethane carcinogenesis
ανά: Siqi Li, κ.ά.
Έκδοση: (2020-04-01)

Novel KRAS gene mutations in sporadic colorectal cancer.
ανά: Walid M Naser, κ.ά.
Έκδοση: (2014-01-01)

Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients
ανά: Carlos E. Bacchi, κ.ά.
Έκδοση: (2012-01-01)

Role of silent mutations in KRAS-mutant tumors
ανά: Jun Lu, κ.ά.
Έκδοση: (2025-02-01)

Mutational profile of KRAS-positive colorectal cancer
ανά: E. N. Telysheva, κ.ά.
Έκδοση: (2022-03-01)

Targeting mutated KRAS in the first‐line therapy
ανά: Hideaki Ijichi
Έκδοση: (2024-04-01)

Characterization of KRAS Mutational Regression in Oligometastatic Patients
ανά: Alessandro Ottaiano, κ.ά.
Έκδοση: (2022-07-01)

KRAS and TP53 mutations in colorectal carcinoma
ανά: Al-Kuraya Khawla
Έκδοση: (2009-01-01)

Mutations of the KRAS oncogene in endometrial hyperplasia and carcinoma.
ανά: Wiesława Niklińska, κ.ά.
Έκδοση: (2009-05-01)

KRAS mutation: from undruggable to druggable in cancer
ανά: Lamei Huang, κ.ά.
Έκδοση: (2021-11-01)

The value of KRAS mutation testing with CEA for the diagnosis of pancreatic mucinous cysts
ανά: Abdurrahman Kadayifci, κ.ά.
Έκδοση: (2016-03-01)

Computational analysis of KRAS mutations: implications for different effects on the KRAS p.G12D and p.G13D mutations.
ανά: Chih-Chieh Chen, κ.ά.
Έκδοση: (2013-01-01)

KRAS Mutation Subtypes and Their Association with Other Driver Mutations in Oncogenic Pathways
ανά: Koushik Mondal, κ.ά.
Έκδοση: (2024-07-01)

Targeting KRAS mutations in pancreatic cancer: opportunities for future strategies
ανά: Anna Linehan, κ.ά.
Έκδοση: (2024-03-01)

Concomitant KRAS mutations attenuate sensitivity of non-small cell lung cancer cells to KRAS G12C inhibition
ανά: Tereza Vaclova, κ.ά.
Έκδοση: (2022-02-01)

Prognostic Implication of KRAS G12C Mutation in a Real-World KRAS-Mutated Stage IV NSCLC Cohort Treated With Immunotherapy in The Netherlands
ανά: Anneloes L. Noordhof, MD, κ.ά.
Έκδοση: (2023-09-01)

Canadian Consensus Recommendations on the Management of KRAS G12C-Mutated NSCLC
ανά: Parneet K. Cheema, κ.ά.
Έκδοση: (2023-07-01)

KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib.
ανά: William Pao, κ.ά.
Έκδοση: (2005-01-01)

Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape
ανά: Brian D. Ratnasinghe, κ.ά.
Έκδοση: (2023-01-01)

Clinicopathologic features and KRAS mutation incidence of gastric carcinomas
ανά: Didar Gürsoy, κ.ά.
Έκδοση: (2022-01-01)

KRAS Gene Mutations and Gender Differences in Colorectal Cancer
ανά: Dmitriy I. Vodolazhskiy, κ.ά.
Έκδοση: (2015-03-01)

Detection and Analysis of EGFR and KRAS Mutation with Lung Adenocarcinoma
ανά: Hui ZHANG, κ.ά.
Έκδοση: (2015-11-01)

IMPACT OF KRAS MUTATIONS IN CLINICAL FEATURES IN COLORECTAL CANCER
ανά: Renato Morato ZANATTO, κ.ά.
Έκδοση: (2020-12-01)

Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations
ανά: Satoshi Inoue, κ.ά.
Έκδοση: (2019-12-01)

Diameter of Superior Rectal Vein – CT Predictor of KRAS Mutation in Rectal Carcinoma
ανά: Song C, κ.ά.
Έκδοση: (2020-10-01)

KRAS mutations in patients with AML: clinical characteristics and not reported mutations using NGS
ανά: Salma Said Ibrahim Elsayed, κ.ά.
Έκδοση: (2024-12-01)

Impact of KRAS mutations and co-mutations on clinical outcomes in pancreatic ductal adenocarcinoma
ανά: Abdelrahman Yousef, κ.ά.
Έκδοση: (2024-02-01)

Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
ανά: Justine Bellier, κ.ά.
Έκδοση: (2020-02-01)