Influence of homoarginine on creatine accumulation and biosynthesis in the mouse

Organisms obtain creatine from their diet or by de novo synthesis via AGAT (L-arginine:glycine amidinotransferase) and GAMT (Guanidinoacetate N-methyltrasferase) in kidney and liver, respectively. AGAT also synthesizes homoarginine (hArg), low levels of which predict poor outcomes in human cardiovas...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Lygate, CA, Lake, HA, McAndrew, DJ, Neubauer, S, Zervou, S
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: Frontiers Media 2022