Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling.

Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling.

The 2-oxoglutarate (2OG) and ferrous iron dependent oxygenases are a superfamily of enzymes that catalyse a wide range of reactions including hydroxylations, desaturations and oxidative ring closures. Recently, it has been discovered that they act as sensors in the hypoxic response in humans and oth...

Полное описание

Библиографические подробности
Главные авторы:	Hewitson, K, Granatino, N, Welford, R, McDonough, M, Schofield, C
Формат:	Journal article
Язык:	English
Опубликовано:	2005

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