Crystal structure of rhodocytin, a ligand for the platelet-activating receptor CLEC-2.

Binding of the snake venom protein rhodocytin to CLEC-2, a receptor on the surface of human platelets, initiates a signaling cascade leading to platelet activation and aggregation. We have previously solved the structure of CLEC-2. The 2.4 A resolution crystal structure of rhodocytin presented here...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Watson, A, Eble, J, O'Callaghan, C
التنسيق: Journal article
اللغة:English
منشور في: 2008