Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase.
Poly(ADP-ribosyl)ation is a reversible post-translational protein modification involved in the regulation of a number of cellular processes including DNA repair, chromatin structure, mitosis, transcription, checkpoint activation, apoptosis and asexual development. The reversion of poly(ADP-ribosyl)a...
Hauptverfasser: | , , , , , , , , |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2012
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