Simultaneous and enantiospecific quantification of primaquine and carboxyprimaquine in human plasma using liquid chromatography-tandem mass spectrometry

Simultaneous and enantiospecific quantification of primaquine and carboxyprimaquine in human plasma using liquid chromatography-tandem mass spectrometry

Background The enantiomers of the 8-aminoquinoline anti-malarial primaquine have different pharmacological properties. Development of an analytical method for simultaneous quantification of the enantiomers of primaquine and its metabolite, carboxyprimaquine, will support clinical pharmacometric asse...

Полное описание

Библиографические подробности
Главные авторы:	Hanpithakpong, W, Day, NPJ, White, NJ, Tarning, J
Формат:	Journal article
Язык:	English
Опубликовано:	BioMed Central 2022

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