Simultaneous and enantiospecific quantification of primaquine and carboxyprimaquine in human plasma using liquid chromatography-tandem mass spectrometry
Background The enantiomers of the 8-aminoquinoline anti-malarial primaquine have different pharmacological properties. Development of an analytical method for simultaneous quantification of the enantiomers of primaquine and its metabolite, carboxyprimaquine, will support clinical pharmacometric asse...
| Главные авторы: | , , , |
|---|---|
| Формат: | Journal article |
| Язык: | English |
| Опубликовано: |
BioMed Central
2022
|