Access to a guanacastepene and cortistatin-related skeleton via ethynyl lactone Ireland−Claisen rearrangement and transannular (4 + 3)-cycloaddition of an azatrimethylenemethane diyl
Heating a 2,5-furanocyclic (2-azidoethyl)allene initiates a cascade reaction comprising azide–allene cycloaddition, loss of nitrogen, and azatrimethylenemethane (ATMM) diyl–furan transannular (4+3)-cycloaddition. The major product of this reaction contains the pentacyclic core common to guanacastepe...
| Hlavní autoři: | , , , |
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| Médium: | Journal article |
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American Chemical Society
2017
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