Transcriptional interference and termination between duplicated alpha-globin gene constructs suggests a novel mechanism for gene regulation.

Transcriptional interference and termination between duplicated alpha-globin gene constructs suggests a novel mechanism for gene regulation.

The interesting possibility that transcriptional interference can occur between eukaryotic genes was raised by studies on the avian leukosis retrovirus (ALV) which showed that deletion of the promoter in the 5' long terminal repeat (LTR) activates the 3' LTR promoter, linked to a downstrea...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteur:	Proudfoot, N
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	1986

Gelijkaardige items

The structure of a human alpha-globin pseudogene and its relationship to alpha-globin gene duplication.
door: Proudfoot, N, et al.
Gepubliceerd in: (1980)

Transcriptional promiscuity of the human alpha-globin gene.
door: Whitelaw, E, et al.
Gepubliceerd in: (1989)

Transcriptional activity of the human pseudogene psi alpha globin compared with alpha globin, its functional gene counterpart.
door: Whitelaw, E, et al.
Gepubliceerd in: (1983)

Studies on messenger RNA 3' end formation in globin genes: a transcriptional interference model for globin gene switching.
door: Proudfoot, N, et al.
Gepubliceerd in: (1985)

Transcriptional regulation of human zeta and psi zeta globin genes.
door: Norman, C, et al.
Gepubliceerd in: (1987)

Transcriptional analysis of human zeta globin genes.
door: Proudfoot, N, et al.
Gepubliceerd in: (1984)

The primary transcription unit of the human alpha 2 globin gene defined by quantitative RT/PCR.
door: Owczarek, C, et al.
Gepubliceerd in: (1992)

The transcriptional regulation of the zeta-globin gene
door: Liu, S
Gepubliceerd in: (2022)

Structure and in vitro transcription of human globin genes.
door: Proudfoot, N, et al.
Gepubliceerd in: (1980)

Intergenic transcription in the human beta-globin gene cluster.
door: Plant, K, et al.
Gepubliceerd in: (2001)

Transcriptional and translational analysis of the human theta globin gene.
door: Leung, S, et al.
Gepubliceerd in: (1989)

Nucleotide sequence of the 3' terminal third of rabbit alpha-globin messenger RNA: comparison with human alpha-globin messenger RNA.
door: Proudfoot, N, et al.
Gepubliceerd in: (1977)

The 3' terminal sequences of human alpha and beta globin messenger RNAs: comparison with rabbit globin messenger RNA.
door: Proudfoot, N, et al.
Gepubliceerd in: (1976)

Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Ggamma-globin gene.
door: Plant, K, et al.
Gepubliceerd in: (2005)

Long-range regulation of alpha-globin gene expression.
door: Higgs, D, et al.
Gepubliceerd in: (2008)

Independent recombination events between the duplicated human alpha globin genes; implications for their concerted evolution.
door: Higgs, D, et al.
Gepubliceerd in: (1984)

Globin gene transcripts can utilize histone gene 3' end processing signals.
door: Whitelaw, E, et al.
Gepubliceerd in: (1986)

GEOGRAPHIC-DISTRIBUTION OF ALPHA-GLOBIN AND BETA-GLOBIN GENE-CLUSTER POLYMORPHISMS
door: Wainscoat, J, et al.
Gepubliceerd in: (1989)

Negative regulation of the human embryonic globin genes zeta and epsilon.
door: Lamb, P, et al.
Gepubliceerd in: (1989)

Dicer-dependent turnover of intergenic transcripts from the human beta-globin gene cluster.
door: Haussecker, D, et al.
Gepubliceerd in: (2005)

Understanding alpha-globin gene regulation: Aiming to improve the management of thalassemia.
door: Higgs, D, et al.
Gepubliceerd in: (2005)

Long-range regulation of alpha globin gene expression during erythropoiesis.
door: Higgs, D, et al.
Gepubliceerd in: (2008)

Tissue-specific histone modification and transcription factor binding in alpha globin gene expression.
door: De Gobbi, M, et al.
Gepubliceerd in: (2007)

Distinct negative regulation of the human embryonic globin genes zeta and epsilon.
door: Watt, P, et al.
Gepubliceerd in: (1993)

Molecular cloning of human epsilon-globin gene.
door: Proudfoot, N, et al.
Gepubliceerd in: (1979)

Molecular rearrangements of the human alpha-globin gene cluster.
door: Higgs, D, et al.
Gepubliceerd in: (1985)

COMPARISON OF THE ALPHA-GLOBIN GENE-CLUSTER STRUCTURE IN PERISSODACTYLA
door: Flint, J, et al.
Gepubliceerd in: (1990)

Alpha Thalassemia in Istanbul: Distribution of Deletions in Alpha-globin Gene Cluster
door: Fatma Nihal Öztürk
Gepubliceerd in: (2024-06-01)

The primary structure of the human epsilon-globin gene.
door: Baralle, F, et al.
Gepubliceerd in: (1980)

Understanding regulation of zeta-globin transcription as the first step towards embryonic globin induction in patients with severe alpha-thalassemia
door: Songdej, D
Gepubliceerd in: (2015)

The role of distal regulatory elements in alpha globin transcription
door: Hay, D
Gepubliceerd in: (2014)

The evolution of the alpha- and beta-globin gene clusters in human populations.
door: Hill, A, et al.
Gepubliceerd in: (1986)

The organization of the tadpole and adult alpha globin genes of Xenopus laevis.
door: Patient, R, et al.
Gepubliceerd in: (1982)

Analysis of the human alpha-globin gene cluster in transgenic mice.
door: Sharpe, J, et al.
Gepubliceerd in: (1993)

GLOBIN GENES AND MESSENGER-RNA FROM HUMANS WITH THALASSEMIA
door: Proudfoot, N, et al.
Gepubliceerd in: (1979)

Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals
door: Warren Wesley C, et al.
Gepubliceerd in: (2008-07-01)

The developmental regulation of the human zeta-globin gene in transgenic mice employing beta-galactosidase as a reporter gene.
door: Pondel, MD, et al.
Gepubliceerd in: (1992)

Characterization of a novel HBB:c.194dup variant of the -globin gene combined with six alpha genes
door: Jungao Huang, et al.
Gepubliceerd in: (2022-05-01)

The gene for theta-globin is transcribed in human fetal erythroid tissues.
door: Leung, S, et al.
Gepubliceerd in: (1987)

The 5' flanking region of human epsilon-globin gene.
door: Baralle, F, et al.
Gepubliceerd in: (1980)