Platelet-derived growth factor-beta receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing.
Connective tissue remodeling provides mammals with a rapid mechanism to repair wounds after injury. Inappropriate activation of this reparative process leads to scarring and fibrosis. Here, we studied the effects of platelet-derived growth factor receptor-beta blockade in vivo using the platelet-der...
Автори: | Rajkumar, V, Shiwen, X, Bostrom, M, Leoni, P, Muddle, J, Ivarsson, M, Gerdin, B, Denton, C, Bou-Gharios, G, Black, C, Abraham, D |
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Формат: | Journal article |
Мова: | English |
Опубліковано: |
2006
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