Investigating the function of microtubule-associated protein tau (MAPT) and its genetic association with Parkinson’s using human iPSC-derived dopamine neurons
<p>Parkinson's disease (PD) primarily manifests as loss of motor control through the degeneration of nigrostriatal dopaminergic neurons. The microtubule-associated protein tau (<em>MAPT</em>) locus is highly genetically associated with PD, wherein the H1 haplotype confers dise...
المؤلف الرئيسي: | Beevers, J |
---|---|
مؤلفون آخرون: | Wade-Martins, R |
التنسيق: | أطروحة |
اللغة: | English |
منشور في: |
2016
|
الموضوعات: |
مواد مشابهة
-
Studying α-Synuclein pathology using iPSC-derived dopaminergic neurons
حسب: Zambon, F
منشور في: (2017) -
RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes
حسب: Heather D.E. Booth, وآخرون
منشور في: (2019-09-01) -
Long-Term Evaluation of Intranigral Transplantation of Human iPSC-Derived Dopamine Neurons in a Parkinson’s Disease Mouse Model
حسب: Sébastien Brot, وآخرون
منشور في: (2022-05-01) -
Aberrant epigenome in iPSC‐derived dopaminergic neurons from Parkinson's disease patients
حسب: Rubén Fernández‐Santiago, وآخرون
منشور في: (2015-10-01) -
Understanding retinal tau pathology through functional 2D and 3D iPSC-derived in vitro retinal models
حسب: Lorenza Mautone, وآخرون
منشور في: (2025-01-01)