Investigating the function of microtubule-associated protein tau (MAPT) and its genetic association with Parkinson’s using human iPSC-derived dopamine neurons

Investigating the function of microtubule-associated protein tau (MAPT) and its genetic association with Parkinson’s using human iPSC-derived dopamine neurons

<p>Parkinson's disease (PD) primarily manifests as loss of motor control through the degeneration of nigrostriatal dopaminergic neurons. The microtubule-associated protein tau (<em>MAPT</em>) locus is highly genetically associated with PD, wherein the H1 haplotype confers dise...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Beevers, J
Rannpháirtithe:	Wade-Martins, R
Formáid:	Tráchtas
Teanga:	English
Foilsithe / Cruthaithe:	2016
Ábhair:	Neurodegeneration Parkinson's disease Induced pluripotent stem cells

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