Investigating the function of microtubule-associated protein tau (MAPT) and its genetic association with Parkinson’s using human iPSC-derived dopamine neurons

<p>Parkinson's disease (PD) primarily manifests as loss of motor control through the degeneration of nigrostriatal dopaminergic neurons. The microtubule-associated protein tau (<em>MAPT</em>) locus is highly genetically associated with PD, wherein the H1 haplotype confers dise...

Повний опис

Бібліографічні деталі
Автор: Beevers, J
Інші автори: Wade-Martins, R
Формат: Дисертація
Мова:English
Опубліковано: 2016
Предмети:

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