Investigating the function of microtubule-associated protein tau (MAPT) and its genetic association with Parkinson’s using human iPSC-derived dopamine neurons

Investigating the function of microtubule-associated protein tau (MAPT) and its genetic association with Parkinson’s using human iPSC-derived dopamine neurons

<p>Parkinson's disease (PD) primarily manifests as loss of motor control through the degeneration of nigrostriatal dopaminergic neurons. The microtubule-associated protein tau (<em>MAPT</em>) locus is highly genetically associated with PD, wherein the H1 haplotype confers dise...

Mô tả đầy đủ

Chi tiết về thư mục
Tác giả chính:	Beevers, J
Tác giả khác:	Wade-Martins, R
Định dạng:	Luận văn
Ngôn ngữ:	English
Được phát hành:	2016
Những chủ đề:	Neurodegeneration Parkinson's disease Induced pluripotent stem cells

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