Inhibition of glycogen breakdown by imino sugars in vitro and in vivo.

Inhibition of glycogen breakdown by imino sugars in vitro and in vivo.

The imino sugar N-butyldeoxynojirimycin (NB-DNJ) is a glucose analogue which inhibits the glycoprotein N-glycan processing enzymes alpha-glucosidases I and II and the ceramide glucosyltransferase that catalyses the first step of glycosphingolipid biosynthesis. This and other N-alkylated DNJ compound...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Andersson, U, Reinkensmeier, G, Butters, T, Dwek, R, Platt, F
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2004

समान संसाधन

Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses.
द्वारा: Butters, T, और अन्य
प्रकाशित: (2005)

Therapeutic applications of imino sugars in lysosomal storage disorders.
द्वारा: Butters, T, और अन्य
प्रकाशित: (2003)

Imino sugar therapy for type 1 Gaucher disease.
द्वारा: Priestman, D, और अन्य
प्रकाशित: (2000)

Membrane disruption and cytotoxicity of hydrophobic N-alkylated imino sugars is independent of the inhibition of protein and lipid glycosylation.
द्वारा: Mellor, H, और अन्य
प्रकाशित: (2003)

Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis
द्वारा: Butters, T, और अन्य
प्रकाशित: (2000)

Lysosomal storage of oligosaccharide and glycosphingolipid in imino sugar treated cells.
द्वारा: Boomkamp, S, और अन्य
प्रकाशित: (2010)

Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: therapeutic implications.
द्वारा: Mehta, A, और अन्य
प्रकाशित: (2001)

High-performance cation-exchange chromatography and pulsed amperometric detection for the separation, detection, and quantitation of N-alkylated imino sugars in biological samples.
द्वारा: Mellor, H, और अन्य
प्रकाशित: (2000)

N-butyldeoxygalactonojirimycin: a more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin, in vitro and in vivo.
द्वारा: Andersson, U, और अन्य
प्रकाशित: (2000)

Reversible infertility in male mice after oral administration of alkylated imino sugars: a nonhormonal approach to male contraception.
द्वारा: van der Spoel, A, और अन्य
प्रकाशित: (2002)

Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents
द्वारा: Zitzmann, N, और अन्य
प्रकाशित: (1999)

Alkylated imino sugars, reversible male infertility-inducing agents, do not change the genetic integrity of male mouse germ cells, despite severe deformities of spermatozoal structures.
द्वारा: Suganuma, R, और अन्य
प्रकाशित: (2004)

SYNTHESIS OF 1,5-DIDEOXY-3-O-(ALPHA-D-MANNOPYRANOSYL)-1,5-IMINO-D-MANNITOL AND 1,5-DIDEOXY-3-O-(ALPHA-D-GLUCOPYRANOSYL)-1,5-IMINO-D-MANNITOL - POWERFUL INHIBITORS OF ENDOMANNOSIDASE
द्वारा: Ardron, H, और अन्य
प्रकाशित: (1993)

Alkylated imino sugars, reversible male infertility-inducing agents, do not affect the genetic integrity of male mouse germ cells during short-term treatment despite induction of sperm deformities.
द्वारा: Suganuma, R, और अन्य
प्रकाशित: (2005)

Inhibition of glycosphingolipid biosynthesis: application to lysosomal storage disorders.
द्वारा: Butters, T, और अन्य
प्रकाशित: (2000)

High-performance liquid chromatography analysis of ganglioside carbohydrates at the picomole level after ceramide glycanase digestion and fluorescent labeling with 2-aminobenzamide.
द्वारा: Wing, DR, और अन्य
प्रकाशित: (2001)

Differential sensitivity of mouse strains to an N-alkylated imino sugar: glycosphingolipid metabolism and acrosome formation.
द्वारा: van der Spoel, A, और अन्य
प्रकाशित: (2008)

DISCOVERY OF A SELECTIVE LYSOSOMAL ALPHA-MANNOSIDASE INHIBITOR FROM AN IMINO-SUGAR LIBRARY
द्वारा: Chang, Y, और अन्य
प्रकाशित: (2014)

Novel di-branched monosaccharides and imino sugars
द्वारा: Barker, K, और अन्य
प्रकाशित: (2009)

2-Acetamido-N-benzyl-1,4-imino-1,2,4-trideoxy-L-ribitol
द्वारा: Harding, C, और अन्य
प्रकाशित: (2005)

New developments in treating glycosphingolipid storage diseases.
द्वारा: Platt, F, और अन्य
प्रकाशित: (2005)

Substrate reduction therapy in mouse models of the glycosphingolipidoses.
द्वारा: Platt, F, और अन्य
प्रकाशित: (2003)

Inhibition of glucosylceramide synthase does not reverse drug resistance in cancer cells.
द्वारा: Norris-Cervetto, E, और अन्य
प्रकाशित: (2004)

Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy.
द्वारा: Jonathan Zirin, और अन्य
प्रकाशित: (2013-11-01)

2-Acetamido-N-benzyl-1,4-imino-1,2,4-trideoxy-L-arabinitol 0.33-hydrate
द्वारा: Harding, C, और अन्य
प्रकाशित: (2005)

Inhibition of cell wall-associated enzymes in vitro and in vivo with sugar analogs.
द्वारा: Nagahashi, G, और अन्य
प्रकाशित: (1990)

New therapeutics for the treatment of glycosphingolipid lysosomal storage diseases.
द्वारा: Butters, T, और अन्य
प्रकाशित: (2003)

Iminosugar inhibitors for treating the lysosomal glycosphingolipidoses
द्वारा: Butters, T, और अन्य
प्रकाशित: (2005)

Inhibition of membrane-associated viral replication
द्वारा: Block, T, और अन्य
प्रकाशित: (2016)

Hexacosylidenecyclohexane inhibits enzymatic breakdown of dietary sugars and modulates glucose homeostasis
द्वारा: Kavishankar Gawli, और अन्य
प्रकाशित: (2022-05-01)

Cellular effects of deoxynojirimycin analogues: uptake, retention and inhibition of glycosphingolipid biosynthesis.
द्वारा: Mellor, H, और अन्य
प्रकाशित: (2004)

Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP
द्वारा: Maria A. Schumacher, और अन्य
प्रकाशित: (2022-10-01)

The role of skeletal muscle glycogen breakdown for regulation of insulin sensitivity by exercise
द्वारा: Jørgen eJensen, और अन्य
प्रकाशित: (2011-12-01)

Triazole carboxylic acids as anionic sugar mimics? Inhibition of glycogen phosphorylase by a D-glucotriazole carboxylate
द्वारा: Krulle, T, और अन्य
प्रकाशित: (1997)

Human GM3 synthase deficiency: Autosomal recessive infantile onset symptomatic epilepsy syndrome.
द्वारा: Priestman, D, और अन्य
प्रकाशित: (2004)

Human GM3 synthase deficiency: A novel form of hereditary childhood epilepsy
द्वारा: Priestman, D, और अन्य
प्रकाशित: (2005)

Introduction
द्वारा: Dwek, R, और अन्य
प्रकाशित: (2003)

Glycolipids in cell biology and medicine - Introduction
द्वारा: Dwek, R, और अन्य
प्रकाशित: (2003)

Cellular effects of deoxynojirimycin analogues: inhibition of N-linked oligosaccharide processing and generation of free glucosylated oligosaccharides.
द्वारा: Mellor, H, और अन्य
प्रकाशित: (2004)

Improved outcome of N-butyldeoxygalactonojirimycin-mediated substrate reduction therapy in a mouse model of Sandhoff disease.
द्वारा: Andersson, U, और अन्य
प्रकाशित: (2004)