Activation of the HIF pathway in cancer.

Activation of the HIF pathway in cancer.

The maintenance of oxygen homeostasis is required both in physiological development and tumour growth. Hypoxia inducible factor (HIF) plays a central role in both processes. Reliable methods for visualising HIF alpha subunits have established that HIF activation occurs in the majority of common canc...

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Bibliographic Details
Main Authors:	Maxwell, P, Pugh, C, Ratcliffe, P
Format:	Journal article
Language:	English
Published:	2001

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