Activation of the HIF pathway in cancer.

The maintenance of oxygen homeostasis is required both in physiological development and tumour growth. Hypoxia inducible factor (HIF) plays a central role in both processes. Reliable methods for visualising HIF alpha subunits have established that HIF activation occurs in the majority of common canc...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Maxwell, P, Pugh, C, Ratcliffe, P
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2001