Targeted sequencing for gene discovery and quantification using RNA CaptureSeq.

RNA sequencing (RNAseq) samples the majority of expressed genes infrequently, owing to the large size, complex splicing and wide dynamic range of eukaryotic transcriptomes. This results in sparse sequencing coverage that can hinder robust isoform assembly and quantification. RNA capture sequencing (...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Mercer, T, Clark, M, Crawford, J, Brunck, M, Gerhardt, D, Taft, R, Nielsen, L, Dinger, M, Mattick, J
Format: Journal article
Sprog:English
Udgivet: Nature Publishing Group 2014