Multicentre appraisal of amyotrophic lateral sclerosis biofluid biomarkers shows primacy of blood neurofilament light chain

The routine clinical integration of individualised objective markers of disease activity in those diagnosed with the neurodegenerative disorder amyotrophic lateral sclerosis is a key requirement for therapeutic development. A large, multi-centre, clinic-based, longitudinal cohort was used to systema...

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Main Authors: Thompson, AG, Gray, E, Verber, N, Bobeva, Y, Lombardi, V, Shepheard, SR, Yildiz, O, Feneberg, E, Farrimond, L, Dharmadasa, T, Gray, P, Edmond, EC, Scaber, J, Gagliardi, D, Kirby, J, Jenkins, TM, Fratta, P, McDermott, CJ, Manohar, SG, Talbot, K, Malaspina, A, Shaw, PJ, Turner, MR
Format: Journal article
Language:English
Published: Oxford University Press 2022