Multicentre appraisal of amyotrophic lateral sclerosis biofluid biomarkers shows primacy of blood neurofilament light chain

The routine clinical integration of individualised objective markers of disease activity in those diagnosed with the neurodegenerative disorder amyotrophic lateral sclerosis is a key requirement for therapeutic development. A large, multi-centre, clinic-based, longitudinal cohort was used to systema...

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Détails bibliographiques
Auteurs principaux: Thompson, AG, Gray, E, Verber, N, Bobeva, Y, Lombardi, V, Shepheard, SR, Yildiz, O, Feneberg, E, Farrimond, L, Dharmadasa, T, Gray, P, Edmond, EC, Scaber, J, Gagliardi, D, Kirby, J, Jenkins, TM, Fratta, P, McDermott, CJ, Manohar, SG, Talbot, K, Malaspina, A, Shaw, PJ, Turner, MR
Format: Journal article
Langue:English
Publié: Oxford University Press 2022