The three methyls: the function and therapeutic potential of histone H3K36 trimethylation

<p>DNA is wrapped around proteins called histones, whose modification regulates numerous cellular processes. Therefore it is not surprising that mutations in the genes that modify the histones are frequently associated with human cancer. For example, mutations in <em>SETD2</em>, en...

Полное описание

Библиографические подробности
Главный автор: Pfister, SX
Другие авторы: Humphrey, T
Формат: Диссертация
Язык:English
Опубликовано: 2014
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