Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins.
OBJECTIVE: Impaired endothelial function, characterized by nitric oxide scavenging by increased superoxide production, is a hallmark of vascular disease states. However, molecular mechanisms regulating superoxide production in human blood vessels remain poorly defined. METHODS AND RESULTS: We compa...
Hauptverfasser: | Guzik, T, Sadowski, J, Kapelak, B, Jopek, A, Rudzinski, P, Pillai, R, Korbut, R, Channon, K |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2004
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