Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding.
The RNA polymerase of influenza A virus is a heterotrimeric complex of PB1, PB2 and PA subunits that is required for transcription and replication of the viral genome. Here, we demonstrate a differential requirement of the PA subunit for binding to the vRNA and cRNA promoters--specifically, PA is mo...
المؤلفون الرئيسيون: | Maier, H, Kashiwagi, T, Hara, K, Brownlee, G |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2008
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مواد مشابهة
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In vitro transcription and polymerase binding studies of the termini of influenza A virus cRNA: evidence for a cRNA panhandle.
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Different de novo initiation strategies are used by influenza virus RNA polymerase on its cRNA and viral RNA promoters during viral RNA replication.
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The N-terminal region of the PA subunit of the RNA polymerase of influenza A/HongKong/156/97 (H5N1) influences promoter binding.
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