Transforming growth factor-beta induces osteoclast formation in the absence of RANKL.
Transforming growth factor beta (TGFbeta) is a multifunctional growth factor that is produced by many cells in bone and is abundant in the bone matrix. TGFbeta is known to regulate RANKL-induced osteoclast formation and bone resorbing activity. In this study we sought to determine whether TGFbeta co...
Hlavní autoři: | Itonaga, I, Sabokbar, A, Sun, S, Kudo, O, Danks, L, Ferguson, D, Fujikawa, Y, Athanasou, N |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2004
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