The role of the priming loop in influenza A virus RNA synthesis

The role of the priming loop in influenza A virus RNA synthesis

RNA-dependent RNA polymerases (RdRps) are used by RNA viruses to replicate and transcribe their RNA genomes1 . They adopt a closed, right-handed fold with conserved subdomains called palm, fingers and thumb1,2. Conserved RdRp motifs A–F coordinate the viral RNA template, NTPs and magnesium ions to f...

書誌詳細
主要な著者:	Te Velthuis, A, Robb, N, Kapanidis, A, Fodor, E
フォーマット:	Journal article
出版事項:	Nature 2016

類似資料

Single-molecule analysis of the influenza virus replication initiation mechanism
著者:: Robb, N, 等
出版事項: (2018)

Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis
著者:: Fodor, E, 等
出版事項: (2016)

Real-time analysis of single influenza virus replication complexes reveals large promoter-dependent differences in initiation dynamics
著者:: Robb, N, 等
出版事項: (2019)

Single-molecule FRET reveals the pre-initiation and initiation conformations of influenza virus promoter RNA
著者:: Robb, N, 等
出版事項: (2016)

Single-molecule FRET reveals a corkscrew RNA structure for the polymerase-bound influenza virus promoter.
著者:: Tomescu, A, 等
出版事項: (2014)

The role of the PB2 627-domain in influenza A virus polymerase function
著者:: Nilsson, B, 等
出版事項: (2017)

Characterizing Influenza a RNA Polymerase - Promoter Interaction using Ensemble Fluorescence Spectroscopy
著者:: Tomescu, A, 等
出版事項: (2013)

Structure and function of the influenza virus transcription and replication machinery
著者:: Fodor, E, 等
出版事項: (2019)

The RNA-dependent RNA polymerase of the influenza A virus
著者:: Stubbs, T, 等
出版事項: (2014)

Influenza Virus RNA Synthesis and the Innate Immune Response
著者:: Sabrina Weis, 等
出版事項: (2021-04-01)

Uncoupling of influenza A virus transcription and replication through mutation of the unpaired adenosine in the viral RNA promoter.
著者:: te Velthuis, A, 等
出版事項: (2013)

NS2/NEP protein regulates transcription and replication of the influenza virus RNA genome
著者:: Robb, N, 等
出版事項: (2009)

NS2/NEP protein regulates transcription and replication of the influenza virus RNA genome.
著者:: Robb, N, 等
出版事項: (2009)

Splicing of influenza A virus NS1 mRNA is independent of the viral NS1 protein.
著者:: Robb, N, 等
出版事項: (2010)

The role of the influenza virus RNA polymerase in host shut-off.
著者:: Vreede, F, 等
出版事項: (2010)

The accumulation of influenza A virus segment 7 spliced mRNAs is regulated by the NS1 protein
著者:: Robb, N, 等
出版事項: (2012)

The accumulation of influenza A virus segment 7 spliced mRNAs is regulated by the NS1 protein.
著者:: Robb, N, 等
出版事項: (2012)

The RNA polymerase of influenza a virus: mechanisms of viral transcription and replication.
著者:: Fodor, E
出版事項: (2013)

Decoding the Role of Temperature in RNA Virus Infections
著者:: Karishma Bisht, 等
出版事項: (2022-10-01)

Functional analysis of the influenza virus H5N1 nucleoprotein tail loop reveals amino acids that are crucial for oligomerization and ribonucleoprotein activities.
著者:: Chan, W, 等
出版事項: (2010)

Functional analysis of the influenza virus H5N1 nucleoprotein tail loop reveals amino acids that are crucial for oligomerization and ribonucleoprotein activities
著者:: Chan, W, 等
出版事項: (2010)

Interplay between influenza virus and the host RNA polymerase II transcriptional machinery
著者:: Walker, A, 等
出版事項: (2019)

Association of the influenza A virus RNA-dependent RNA polymerase with cellular RNA polymerase II.
著者:: Engelhardt, O, 等
出版事項: (2005)

Influenza virus inhibits RNA polymerase II elongation.
著者:: Chan, A, 等
出版事項: (2006)

Characterization of the RNA-fork model of virion RNA in the initiation of transcription in influenza A virus.
著者:: Fodor, E, 等
出版事項: (1995)

NS reassortment of an H7-type highly pathogenic avian influenza virus affects its propagation by altering the regulation of viral RNA production and antiviral host response.
著者:: Wang, Z, 等
出版事項: (2010)

NS reassortment of an H7-type highly pathogenic avian influenza virus affects its propagation by altering the regulation of viral RNA production and antiviral host response
著者:: Wang, Z, 等
出版事項: (2010)

Attenuation of influenza A virus mRNA levels by promoter mutations.
著者:: Fodor, E, 等
出版事項: (1998)

Insight into the multifunctional RNA synthesis machine of rabies virus
著者:: Fodor, E
出版事項: (2020)

Closing and opening of the RNA polymerase trigger loop
著者:: Mazumder, A, 等
出版事項: (2020)

The surface-exposed PA51-72-loop of the influenza A virus polymerase is required for viral genome replication
著者:: Nilsson-Payant, B, 等
出版事項: (2018)

The PB2 subunit of the influenza A virus RNA polymerase is imported into the mitochondrial matrix
著者:: Long, J, 等
出版事項: (2016)

Role of ran binding protein 5 in nuclear import and assembly of the influenza virus RNA polymerase complex.
著者:: Deng, T, 等
出版事項: (2006)

Distinctive features of the respiratory syncytial virus priming loop compared to other non-segmented negative strand RNA viruses.
著者:: Tessa N Cressey, 等
出版事項: (2022-06-01)

Host restriction of influenza virus polymerase activity by PB2 627E is diminished on short viral templates in a nucleoprotein-independent manner.
著者:: Paterson, D, 等
出版事項: (2014)

Mutational analysis of the RNA-fork model of the influenza A virus vRNA promoter in vivo.
著者:: Kim, H, 等
出版事項: (1997)

Emerging roles for the influenza A virus nuclear export protein (NEP).
著者:: Paterson, D, 等
出版事項: (2012)

Mutation of an influenza virus polymerase 3′ RNA promoter binding site inhibits transcription elongation
著者:: Walker, A, 等
出版事項: (2020)

Polyuridylated mRNA synthesized by a recombinant influenza virus is defective in nuclear export.
著者:: Poon, L, 等
出版事項: (2000)

Structural insights into RNA polymerases of negative-sense RNA viruses
著者:: te Velthius, AJW, 等
出版事項: (2021)