The role of the priming loop in influenza A virus RNA synthesis
RNA-dependent RNA polymerases (RdRps) are used by RNA viruses to replicate and transcribe their RNA genomes1 . They adopt a closed, right-handed fold with conserved subdomains called palm, fingers and thumb1,2. Conserved RdRp motifs A–F coordinate the viral RNA template, NTPs and magnesium ions to f...
| Hauptverfasser: | , , , |
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| Format: | Journal article |
| Veröffentlicht: |
Nature
2016
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