A transit-amplifying population underpins the efficient regenerative capacity of the testis.
The spermatogonial stem cell (SSC) that supports spermatogenesis throughout adult life resides within the GFRα1-expressing A type undifferentiated spermatogonia. The decision to commit to spermatogenic differentiation coincides with the loss of GFRα1 and reciprocal gain of Ngn3 (Neurog3) expression....
Main Authors: | Carrieri, C, Comazzetto, S, Grover, A, Morgan, M, Buness, A, Nerlov, C, O'Carroll, D |
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Format: | Journal article |
Language: | English |
Published: |
Rockefeller University Press
2017
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