F-actin-driven CD28-CD80 localization in the immune synapse
During immunological synapse (IS) formation, T cell receptor (TCR) signaling complexes, integrins, and costimulatory molecules exhibit a particular spatial localization. Here, we develop an agent-based model for the IS formation based on TCR peptide-bound major histocompatibility complex (pMHC) and...
Үндсэн зохиолчид: | Siokis, A, Robert, P, Demetriou, P, Dustin, M, Meyer-Hermann, M |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
Elsevier
2018
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Ижил төстэй зүйлс
Ижил төстэй зүйлс
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F-actin driven CD28-CD80 localization in the Immune Synapse
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The immunological synapse and CD28-CD80 interactions.
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CD28-CD80 Interactions Control Regulatory T Cell Motility and Immunological Synapse Formation.
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CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse.
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Characterization of mechanisms positioning costimulatory complexes in immune synapses
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