Refining molecular analysis in the pathways of colorectal carcinogenesis.
BACKGROUND and AIMS: In the stepwise model, specific genetic and epigenetic changes accumulate as colorectal adenomas progress to carcinomas (CRCs). CRCs also acquire global phenotypes, particularly microsatellite instability (MSI) and aneuploidy/polyploidy (chromosomal instability, CIN). Few chang...
প্রধান লেখক: | Rowan, A, Halford, S, Gaasenbeek, M, Kemp, Z, Sieber, O, Volikos, E, Douglas, E, Fiegler, H, Carter, N, Talbot, I, Silver, A, Tomlinson, I |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2005
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