Leukocyte adhesion deficiency II: therapy and genetic defect.
Leukocyte adhesion deficiency II (LAD II) is a rare congenital disease which is caused by a defect in fucosylation of glycoconjugates. Hypofucosylated structures include ligands for the selectin family of adhesion molecules. This results in a leukocyte adhesion defect causing an immunodeficiency. In...
| Main Authors: | , , , |
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| 格式: | Journal article |
| 語言: | English |
| 出版: |
2002
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