N-acyl 'quat' pyrrolidinone auxiliary as a chiral amide equivalent via direct aminolysis

A novel route to chiral amides through the efficient, non-racemising, cleavage of N-acyl side chains from a 'Quat' chiral auxiliary using N-centred nucleophiles is described. The synthetic utility of the procedure is then highlighted by the preparation of a range of succinamide and succini...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Davies, S, Dixon, D
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2002