IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis.

BACKGROUND: IL-1beta has the potential to promote progressive renal disease by effects on macrophage recruitment and activation or by effects mediated through tubular cell transforming growth factor (TGF)-beta production, previously demonstrated in vitro. METHODS: The in vivo roles of endogenous IL...

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Hlavní autoři: Jones, L, O'Sullivan, K, Semple, T, Kuligowski, M, Fukami, K, Ma, F, Nikolic-Paterson, D, Holdsworth, SR, Kitching, A
Médium: Journal article
Jazyk:English
Vydáno: 2009

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