The crystal structure of the catalytic domain of human urokinase-type plasminogen activator.
BACKGROUND: Urokinase-type plasminogen activator (u-PA) promotes fibrinolysis by catalyzing the conversion of plasminogen to the active protease plasmin via the cleavage of a peptide bond. When localized to the external cell surface it contributes to tissue remodelling and cellular migration; inhibi...
| Main Authors: | , , , , , , , |
|---|---|
| 格式: | Journal article |
| 语言: | English |
| 出版: |
1995
|