Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling.

Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling.

A neuronal isoform of nitric oxide synthase (nNOS) has recently been located to the cardiac sarcoplasmic reticulum (SR). Subcellular localization of a constitutive NOS in the proximity of an activating source of Ca2+ suggests that cardiac nNOS-derived NO may regulate contraction by exerting a highly...

Podrobná bibliografie
Hlavní autoři:	Sears, C, Bryant, S, Ashley, E, Lygate, C, Rakovic, S, Wallis, H, Neubauer, S, Terrar, D, Casadei, B
Médium:	Journal article
Jazyk:	English
Vydáno:	2003

Podobné jednotky

A cardiac neuronal nitric oxide synthase isoform regulates contraction and calcium handling in murine ventricular myocytes
Autor: Sears, C, a další
Vydáno: (2002)

A cardiac neuronal nitric oxide synthase isoform regulates contraction and calcium handling in murine ventricular myocytes
Autor: Sears, C, a další
Vydáno: (2002)

A cardiac nitric oxide synthase 1 regulates contraction and calcium fluxes - a novel mechanism in the autocrine control of cardiac function
Autor: Ashley, E, a další
Vydáno: (2002)

Neuronal nitric oxide synthase (NOS1) regulates beta-adrenergic contraction and calcium handling in isolated murine ventricular myocytes
Autor: Zhang, Y, a další
Vydáno: (2003)

Nitric oxide synthase 1 (NOS1) regulates basal and beta-adrenergic left-ventricular contraction and relaxation in vivo
Autor: Ashley, E, a další
Vydáno: (2003)

Nitric oxide synthase 1 (NOS1) regulates basal and beta-adrenergic left ventricular contraction and relaxation in vivo
Autor: Ashley, E, a další
Vydáno: (2003)

Effect of disruption of the nNOS gene on myocardial calcium current and contraction
Autor: Sears, C, a další
Vydáno: (2001)

Electrophysiological and mechanical properties of ventricular myocytes isolated from wild-type mice and mice with disruption of the neuronal nitric oxide synthase gene
Autor: Sears, C, a další
Vydáno: (2001)

Nitric oxide control of cardiac function: is neuronal nitric oxide synthase a key component?
Autor: Sears, C, a další
Vydáno: (2004)

Selective gene deletion of the neuronal nitric oxide synthase (nNOS) accelerates pathological left ventricular remodelling and functional deterioration after myocardial infarction (MI)
Autor: Dawson, D, a další
Vydáno: (2005)

DISTINCTIVE ROLE FOR PROTEIN PHOSPHATASES AND PROTEIN KINASES IN THE REGULATION OF MYOCARDIAL CONTRACTION BY THE NEURONAL NITRIC OXIDE SYNTHASE
Autor: Zhang, Y, a další
Vydáno: (2010)

Enhancement of beta adrenergic responsiveness in myocytes lacking nitric oxide synthase 1
Autor: Ashley, E, a další
Vydáno: (2001)

MODELLING CALCIUM HANDLING MECHANISMS IN NORMAL AND NEURONAL NITRIC OXIDE SYNTHASE KNOCK-OUT MOUSE HEARTS
Autor: Li, L, a další
Vydáno: (2009)

Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes.
Autor: Ashley, E, a další
Vydáno: (2002)

The subcellular localisation of neuronal nitric oxide synthase determines the downstream effects of NO on myocardial function
Autor: Carnicer, R, a další
Vydáno: (2017)

The emerging role of neuronal nitric oxide synthase in the regulation of myocardial function.
Autor: Casadei, B
Vydáno: (2006)

Does nitric oxide regulate the hyperpolarisation-activated inward current in ventricular myocytes from spontaneously hypertensive rats?
Autor: Bryant, S, a další
Vydáno: (2000)

Does nitric oxide regulate the hyperpolarisation-activated inward current in ventricular myocytes from spontaneously hypertensive rats?
Autor: Sears, C, a další
Vydáno: (2000)

Nitric oxide does not modulate the hyperpolarization-activated current, I(f), in ventricular myocytes from spontaneously hypertensive rats.
Autor: Bryant, S, a další
Vydáno: (2001)

Regulation of endothelial nitric-oxide synthase (NOS) S-glutathionylation by neuronal NOS: evidence of a functional interaction between myocardial constitutive NOS isoforms.
Autor: Idigo, W, a další
Vydáno: (2012)

Nitric oxide synthase isoforms play distinct roles during acute peritonitis.
Autor: Ni, J, a další
Vydáno: (2010)

Myocardial NOS1 controls the lusitropic response to beta-adrenergic stimulation in vivo and in vitro
Autor: Sears, C, a další
Vydáno: (2003)

NEURONAL NITRIC OXIDE SYNTHASE GENE DISRUPTION REDUCES THE DIASTOLIC CALCIUM LEAK FROM THE RYANODINE RECEPTOR: IMPLICATIONS FOR EXCITATION-CONTRACTION COUPLING IN HEART FAILURE
Autor: Lim, G, a další
Vydáno: (2009)

The role of nitric oxide synthase isoforms in aged porcine oocytes
Autor: J. Nevoral, a další
Vydáno: (2013-10-01)

Effects of Nitric Oxide Synthase Isoforms During Experimental Tooth Movement
Autor: Hasan Bülbül, a další
Vydáno: (2012-12-01)

Neuronal nitric oxide synthase and human vascular regulation.
Autor: Melikian, N, a další
Vydáno: (2009)

Effects of isoproterenol on calcium transients and calcium sparks in guinea-pig sino-atrial node cells imaged by confocal microscopy
Autor: Jackson, V, a další
Vydáno: (2002)

NEURONAL NITRIC OXIDE SYNTHASE-MEDIATED REGULATION OF MYOCARDIAL REDOX STATE AND beta 3 ADRENERGIC RECEPTOR RESPONSES
Autor: Idigo, W, a další
Vydáno: (2010)

Actions of a membrane permeant analogue of NAADP on contractions and calcium sparks in cardiac ventricular myocytes.
Autor: Rakovic, S, a další
Vydáno: (2007)

Nitric oxide synthases in heart failure.
Autor: Carnicer, R, a další
Vydáno: (2013)

Expression of Constitutive Nitric Oxide Synthase Isoforms in Varicose Vein Wall; Preliminary Results
Autor: Zora Haviarová, a další
Vydáno: (2011-01-01)

Spontaneous pulmonary emphysema in mice lacking all three nitric oxide synthase isoforms
Autor: Kaori Kato, a další
Vydáno: (2021-11-01)

Role of cGMP-inhibited phosphodiesterase and sarcoplasmic calcium in mediating the increase in basal heart rate with nitric oxide donors.
Autor: Musialek, P, a další
Vydáno: (2000)

Neuronal nitric oxide synthase and affective disorders
Autor: Qi-Gang Zhou, a další
Vydáno: (2018-12-01)

Important differences in nitric oxide synthase activity and predominant isoform in reproductive tissues from human and rat
Autor: Al-Hijji J, a další
Vydáno: (2003-02-01)

Calcium transients in guinea-pig sino-atrial node cells imaged by confocal microscopy.
Autor: Rakovic, S, a další
Vydáno: (2000)

Tetrahydrobiopterin protects against hypertrophic heart disease independent of myocardial nitric oxide synthase coupling.
Autor: Hashimoto, T, a další
Vydáno: (2016)

Tetrahydrobiopterin protects against hypertrophic heart disease independent of myocardial nitric oxide synthase coupling
Autor: Hashimoto, T, a další
Vydáno: (2016)

Mechanisms regulating myocardial redox state in chronic atrial fibrillation: the role of NADPH-oxidase and uncoupled nitric oxide synthases
Autor: Margaritis, M, a další
Vydáno: (2010)

Nitric-oxide-mediated regulation of cardiac contractility and stretch responses.
Autor: Casadei, B, a další
Vydáno: (2003)