The anti-malarial drug atovaquone potentiates platinum-mediated cancer cell death by increasing oxidative stress

The anti-malarial drug atovaquone potentiates platinum-mediated cancer cell death by increasing oxidative stress

Platinum chemotherapies are highly effective cytotoxic agents but often induce resistance when used as monotherapies. Combinatorial strategies limit this risk and provide effective treatment options for many cancers. Here, we repurpose atovaquone (ATQ), a well-tolerated & FDA-approved anti-malar...

Bibliografski detalji
Glavni autori:	Coates, JTT, Rodriguez-Berriguete, G, Puliyadi, R, Ashton, T, Prevo, R, Wing, A, Granata, G, Pirovano, G, McKenna, GW, Higgins, GS
Format:	Journal article
Jezik:	English
Izdano:	Springer Nature 2020
Teme:	Chemotherapy Preclinical research

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