The anti-malarial drug atovaquone potentiates platinum-mediated cancer cell death by increasing oxidative stress

The anti-malarial drug atovaquone potentiates platinum-mediated cancer cell death by increasing oxidative stress

Platinum chemotherapies are highly effective cytotoxic agents but often induce resistance when used as monotherapies. Combinatorial strategies limit this risk and provide effective treatment options for many cancers. Here, we repurpose atovaquone (ATQ), a well-tolerated & FDA-approved anti-malar...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Coates, JTT, Rodriguez-Berriguete, G, Puliyadi, R, Ashton, T, Prevo, R, Wing, A, Granata, G, Pirovano, G, McKenna, GW, Higgins, GS
Format:	Journal article
Język:	English
Wydane:	Springer Nature 2020
Hasła przedmiotowe:	Chemotherapy Preclinical research

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