Synergistic complement lysis by monoclonal antibodies to the human leukocyte common antigen requires both the classical and alternative pathways.

Synergistic complement lysis by monoclonal antibodies to the human leukocyte common antigen requires both the classical and alternative pathways.

In a previous study we isolated a series of rat monoclonal antibodies to the human leukocyte common (LC) antigen and demonstrated that synergistic complement lysis was possible between IgG2b antibodies which recognised different epitopes. In this report we have examined the mechanisms that were invo...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Bindon, C, Hale, G, Hughes-Jones, N, Gorick, B, Waldmann, H
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	1987

Những quyển sách tương tự

Therapeutic potential of monoclonal antibodies to the leukocyte-common antigen. Synergy and interference in complement-mediated lysis.
Bằng: Bindon, C, et al.
Được phát hành: (1985)

Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies.
Bằng: Bindon, C, et al.
Được phát hành: (1988)

Therapeutic potential of monoclonal antibodies to the leucocyte common antigen.
Bằng: Bindon, C, et al.
Được phát hành: (1985)

Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen.
Bằng: Xia, M, et al.
Được phát hành: (1993)

Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q.
Bằng: Bindon, C, et al.
Được phát hành: (1988)

Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis.
Bằng: Xia, M, et al.
Được phát hành: (1993)

Blocking of cytotoxic T cell function by monoclonal antibodies against the CD45 antigen (T200/leukocyte-common antigen).
Bằng: Tighe, H, et al.
Được phát hành: (1987)

Complement activation by immunoglobulin does not depend solely on C1q binding.
Bằng: Bindon, C, et al.
Được phát hành: (1990)

Xenotransplanted Pig Sertoli Cells Inhibit Both the Alternative and Classical Pathways of Complement-Mediated Cell Lysis While Pig Islets Are Killed
Bằng: Kandis Wright, et al.
Được phát hành: (2016-11-01)

Monoclonal antibodies to rat leukocyte surface antigens, MHC antigens, and immunoglobulins.
Bằng: Puklavec, M, et al.
Được phát hành: (2001)

Monoclonal antibodies against rat leukocyte surface antigens.
Bằng: van den Berg, T, et al.
Được phát hành: (2001)

RAT MONOCLONAL-ANTIBODIES FOR BONE-MARROW TRANSPLANTATION (BMT) - THE CAMPATH SERIES
Bằng: Waldmann, H, et al.
Được phát hành: (1985)

Purging in auto- and allografts: monoclonal antibodies which use human complement and other natural effector mechanisms.
Bằng: Cobbold, S, et al.
Được phát hành: (1990)

Purging in auto- and allografts: monoclonal antibodies which use human complement and other natural effector mechanisms.
Bằng: Cobbold, S, et al.
Được phát hành: (1990)

Monoclonal antibodies for immunosuppression.
Bằng: Waldmann, H, et al.
Được phát hành: (1988)

Engineering multiple-domain forms of the therapeutic antibody CAMPATH-1H: effects on complement lysis.
Bằng: Greenwood, J, et al.
Được phát hành: (1994)

COMPLEMENT LYSIS MEDIATED BY ENGINEERED MULTIPLE-DOMAIN FORMS OF THE THERAPEUTIC ANTIBODY CAMPATH-1H
Bằng: Greenwood, J, et al.
Được phát hành: (1994)

RAT MONOCLONAL-ANTIBODIES TO PREVENT G-VS-H AND H-VS-G REACTIONS IN BONE-MARROW TRANSPLANTATION
Bằng: Waldmann, H, et al.
Được phát hành: (1986)

Pilot study of CAMPATH-1, a rat monoclonal antibody that fixes human complement, as an immunosuppressant in organ transplantation.
Bằng: Hale, G, et al.
Được phát hành: (1986)

INTERACTION OF MONOCLONAL-ANTIBODIES WITH THE IMMUNE-SYSTEM
Bằng: Clark, M, et al.
Được phát hành: (1986)

Both Monoclonal and Polyclonal Immunoglobulin Contingents Mediate Complement Activation in Monoclonal Gammopathy Associated-C3 Glomerulopathy
Bằng: Sophie Chauvet, et al.
Được phát hành: (2018-10-01)

EFFECTS OF MONOCLONAL-ANTIBODIES OF THE CAMPATH SERIES INVIVO - REQUIREMENTS FOR EFFECTIVE ANTIBODY THERAPY
Bằng: Dyer, M, et al.
Được phát hành: (1988)

The improved lytic function and in vivo efficacy of monovalent monoclonal CD3 antibodies.
Bằng: Clark, M, et al.
Được phát hành: (1989)

Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement.
Bằng: Hale, G, et al.
Được phát hành: (1983)

Human leukocyte differentiation antigens: monoclonal antibody computer databases as a tool for the future.
Bằng: Cobbold, S
Được phát hành: (1987)

Modulation of recognition memory performance by light requires both melanopsin and classical photoreceptors
Bằng: Tam, S, et al.
Được phát hành: (2016)

Synergistic monoclonal antibodies for in vitro immunomodulation of dog islets.
Bằng: Brons, I, et al.
Được phát hành: (1992)

Complement factor H protects tumor cell-derived exosomes from complement-dependent lysis and phagocytosis.
Bằng: Ryan T Bushey, et al.
Được phát hành: (2021-01-01)

Arthrogenicity of type II collagen monoclonal antibodies associated with complement activation and antigen affinity
Bằng: Mizutani Nobuaki, et al.
Được phát hành: (2011-11-01)

Plasmid-encoded toxin of Escherichia coli cleaves complement system proteins and inhibits complement-mediated lysis in vitro
Bằng: Gabriel B. Correa, et al.
Được phát hành: (2024-02-01)

Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW).
Bằng: Cobbold, S, et al.
Được phát hành: (1994)

Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis
Bằng: David A. Spencer, et al.
Được phát hành: (2022-02-01)

CAMPATH-1 monoclonal antibodies in bone marrow transplantation.
Bằng: Hale, G, et al.
Được phát hành: (1994)

Advantages of rat monoclonal antibodies.
Bằng: Clark, M, et al.
Được phát hành: (1983)

Complement Receptors and Their Role in Leukocyte Recruitment and Phagocytosis
Bằng: Sofie Vandendriessche, et al.
Được phát hành: (2021-02-01)

Specificity of monoclonal antibody Campath-1.
Bằng: Hale, G, et al.
Được phát hành: (1988)

Entamoeba histolytica Develops Resistance to Complement Deposition and Lysis after Acquisition of Human Complement-Regulatory Proteins through Trogocytosis
Bằng: Hannah W. Miller, et al.
Được phát hành: (2022-04-01)

Effect of graft perfusion with two CD45 monoclonal antibodies on incidence of kidney allograft rejection.
Bằng: Brewer, Y, et al.
Được phát hành: (1989)

Anti-HLA antibodies with complementary and synergistic interaction geometries promote classical complement activation on platelets
Bằng: Maaike Rijkers, et al.
Được phát hành: (2019-02-01)

Production, selection, and testing of monoclonal antibodies to canine leukocytes in the dog kidney allograft model.
Bằng: Davies, H, et al.
Được phát hành: (1994)